Results 91 to 100 of about 15,396 (289)

Procainamide Is a Specific Inhibitor of DNA Methyltransferase 1*

open access: yesJournal of Biological Chemistry, 2005
CpG island hypermethylation occurs in most cases of cancer, typically resulting in the transcriptional silencing of critical cancer genes. Procainamide has been shown to inhibit DNA methyltransferase activity and reactivate silenced gene expression in ...
Byron H. Lee   +3 more
semanticscholar   +1 more source

Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement

open access: yesAGING MEDICINE, Volume 8, Issue 1, February 2025.
ABSTRACT Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuations, and adverse clinical outcomes, including life ...
Huabing Zhang, Ming Xia Yuan, Qi Pan
wiley   +1 more source

A review on dronedarone: Pharmacological, pharmacodynamic and pharmacokinetic profile

open access: yesJournal of Acute Disease, 2016
Dronedarone, a benzofuran containing chemical compound, is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It is prescribed to the cardiovascular patients who have paroxysmal or persistent atrial fibrillation to lower ...
Farah Iram   +4 more
doaj   +1 more source

Formation of self-organized organic-inorganic hybrids [PDF]

open access: yes, 2015
The morphology features and peculiarities of current-voltage characteristics of selforganized organic–silicon hybrids were investigated. The organic layers were formed by chemical bath deposition at room temperatures of phosphorus doped n-type FZ Si ...
Gorbach, T.   +5 more
core  

Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells.

open access: yesOncology Report, 2009
Secreted Wingless type (Wnt) ligands have previously been shown to be involved in tumor developmental processes and oncogenesis. Aberrant promoter methylation of Wnt inhibitory factor-1 (WIF-1) is a fundamental mechanism of epigenetic silencing in human ...
Zhi Gao   +8 more
semanticscholar   +1 more source

Factors associated with stellate ganglion block success in recurrent ventricular arrhythmias

open access: yesESC Heart Failure, Volume 12, Issue 1, Page 110-117, February 2025.
Abstract Aims One treatment option for refractory ventricular arrythmias is stellate ganglion block (SGB). We examined differences in SGB success by patient and arrhythmia characteristics and predictors of successful SGB. Methods and results This was a multicenter analysis of patients treated for refractory ventricular arrythmias in the Czech Republic ...
Fouad Chouairi   +7 more
wiley   +1 more source

Table of Contents, Volume Nine, 1973 [PDF]

open access: yes, 1973
Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1973, Volume ...

core   +1 more source

The N‐Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case–Control Study

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
CD patients were more likely than controls to have the NAT2*4/5 genotype (OR = 2.77, 95% CI 1.17–6.57). ABSTRACT The enzyme N‐acetyltransferase 2 (NAT2) plays an important role in metabolism and detoxification of xenobiotics, including carcinogens and medications.
Pawel Petryszyn   +9 more
wiley   +1 more source

Bundle Branch Reentrant Ventricular Tachycardia in a Patient with the Brugada Electrocardiographic Pattern

open access: yesAnnals of Noninvasive Electrocardiology, 2003
A 55‐year‐old, previously healthy man presented with an episode of wide QRS tachycardia that had left bundle branch morphology and left superior axis. His electrocardiogram in sinus rhythm showed characteristic Brugada pattern with coved type ST‐segment (
Alexander Mazur   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy