Results 231 to 240 of about 15,396 (289)

Procainamide-lnduced Psychosis

JAMA: The Journal of the American Medical Association, 1978
ALTHOUGH a number of standard textbooks and reference sources indicate that psychosis can occur during procainamide hydrochloride administration, we found few cases of documentation. To our knowledge, the following case report is the first detailed description of such a psychosis.
James R. Guidry, Ivan D. McCrum
openaire   +4 more sources

Procainamide Disposition in Obesity

Drug Intelligence & Clinical Pharmacy, 1983
The pharmacokinetics of intravenous procainamide (PA) were studied in seven obese and seven normal subjects. Serum concentrations and urinary excretion rates of PA and its active metabolite, NAPA, were measured by high performance liquid chromatography. Pharmacokinetic parameters were related to ideal body weight (IBW) and total body weight (TBW). The
William J. Jusko, Cartha Naylor, David R. Conti, Patricia B. Christoff   +3 more
openaire   +3 more sources

Treatment of Myotonia with Procainamide

Archives of Neurology And Psychiatry, 1957
Disappointment in the use of a number of different therapies in the treatment of myotonia has led to the continuing search for more efficacious drugs. Geschwind and Simpson 1 in 1955 reported that procainamide was useful in the treatment of myotonia. The present report attempts to evaluate this drug further.
Walter J. Friedlander, D. Stuart MacROBBIE   +1 more
openaire   +3 more sources

Assignment of Core versus Antenna Fucosylation Types in Protein N-Glycosylation via Procainamide Labeling and Tandem Mass Spectrometry.

Analytical Chemistry, 2015
Fucosylation is an important feature of protein N-glycosylation as it has been reported to influence the efficacy of therapeutic proteins and as a potential disease biomarker.
Charles C. Nwosu, Hoi Kei Yau, S. Becht
semanticscholar   +1 more source

An Unexpected Reaction to Procainamide

JAMA: The Journal of the American Medical Association, 1963
DURING THE DECADE in which procainamide hydrochloride has been used as a cardiac depressant, several types of undesirable side effects have been described. This case report deals with such a reaction and includes some interesting laboratory data obtained during the acute episodes.
John A. King, Robert E. Blount
openaire   +3 more sources

Investigation of Volumetric and Acoustic Properties of Procainamide Hydrochloride in Aqueous Binary and (Water + Amino Acid) Ternary Mixtures at Different Temperatures

, 2017
For effective drug design and development, an integrated process utilizing all available information from structural, thermodynamic, and biological studies plays a very important role.
Doyel M. Bhattacharya, Dinesh V. Kawadkar, C. Pandhurnekar, A. Wankhade, Umesh R. Pratap, S. Zodape   +5 more
semanticscholar   +1 more source

Preparation and Antiproliferative Activity of Liposomes Containing a Combination of Cisplatin and Procainamide Hydrochloride.

Chemical Research in Toxicology, 2016
We have previously reported the enhancement of the antiproliferative and apoptotic activities of cis-diamminedichloroplatinum(II) (DDP) when it is coadministered with a class I antiarrhythmic drug procainamide hydrochloride (PA).
M. Viale, A. Fontana, I. Marić, M. Monticone, Guido Angelini, Carla Gasbarri   +5 more
semanticscholar   +1 more source

Procainamide‐induced thrombocytopenia

American Journal of Hematology, 1984
AbstractAn 81‐year‐old female developed marked thrombocytopenia associated with numerous megakaryocytes in the bone marrow, but without anemia or leukopenia, after taking procainamide (3 g/day) for a period of 2 months. Despite continuation of this medication, treatment with prednisone led to rapid rise in platelet count, and withdrawal of steroid was ...
Rodney E. Kosfeld, Yong K. Liu, Robert Rosenstein, Leonard Leight   +3 more
openaire   +3 more sources

Procainamide‐associated pancytopenia

American Journal of Hematology, 1988
AbstractA 42‐year‐old male developed thrombocytopenia and anemia along with agranulocytosis during treatment with procainamide. Bone marrow hypoplasia was evident on biopsy, and the patient was without evidence of systemic lupus erythematosis. He had prompt marrow recovery on drug withdrawal. While procainamide‐induced agranulocytosis has been reported
Jeffrey A. Berenson, Anthony F. Shields
openaire   +3 more sources

The renal elimination of procainamide

Clinical Pharmacology & Therapeutics, 1976
The question of pR or flow dependence for the renal elimination of procainamide (PCA) was studied under 4 conditions in each of 4 subjects. Each subject received 500 mg of PCA intravenously at weekly intervals while in astate of (1) acid load (NR4Cl) and water deprivation, (2) acid load and water excess, (3) alkali load (NaRCO3) and water deprivation ...
Renato L. Galeazzi, Thomas Lockwood, Leslie Z. Benet, Lewis B. Sheiner   +3 more
openaire   +3 more sources