Results 31 to 40 of about 5,853 (195)

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2236-2255, May 2026.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

Research on Synthesis of New Azo Calix[4]arene and its Dyeing Properties

open access: yesMATEC Web of Conferences, 2015
With the raw materials of calix[4]arene, benzocaine, tricaine and procaine hydrochloride, three new azo calix[4]arene derivatives—6a, 6b and 6c are synthesized by diazotization–coupling reaction of an aromatic amine, with its yield of 83%, 81% and 83 ...
Tang Jun   +4 more
doaj   +1 more source

Neuroprotective Effect of Compound Anisodine in a Mouse Model with Chronic Ocular Hypertension

open access: yesChinese Medical Journal, 2015
Background: Compound anisodine (CA) is a compound preparation made from hydrobromide anisodine and procaine hydrochloride. The former is an M-choline receptor blocker with the function of regulating the vegetative nervous system, improving ...
Wen-Dong Liu   +3 more
doaj   +1 more source

Management of a diaphragmatic hernia using self‐locking knots

open access: yesEquine Veterinary Education, Volume 38, Issue 3, Page e105-e110, March 2026.
Summary A 4‐year‐old Thoroughbred gelding was presented with a history of severe colic signs that were non‐responsive to non‐steroidal anti‐inflammatory drugs. During initial evaluation, distended small intestine was observed, together with continued colic signs and a serosanguinous abdominocentesis sample.
A. Gillen   +4 more
wiley   +1 more source

Effect of Single Dose of Antimicrobial Administration at Birth on Fecal Microbiota Development and Prevalence of Antimicrobial Resistance Genes in Piglets

open access: yesFrontiers in Microbiology, 2019
Optimization of antimicrobial use in swine management systems requires full understanding of antimicrobial-induced changes on the developmental dynamics of gut microbiota and the prevalence of antimicrobial resistance genes (ARGs).
Mohamed Zeineldin   +8 more
doaj   +1 more source

Equine botulism

open access: yesEquine Veterinary Journal, Volume 58, Issue 2, Page 333-347, March 2026.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik   +2 more
wiley   +1 more source

Staphylococcus aureus pneumonia and pararectal abscess in a horse secondary to catheter‐related septic thrombophlebitis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This report describes the development of methicillin‐sensitive Staphylococcus aureus septic jugular thrombophlebitis, pneumonia and a delayed‐onset pararectal abscess secondary to bacterial embolization from intravenous catheterization in a horse and demonstrates the successful treatment of all aspects. A racing Arabian mare was presented with
Tiago Fernandes, Camilla A. Jamieson
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Antimicrobial prescribing guidelines for feedlot cattle

open access: yes
Australian Veterinary Journal, EarlyView.
P Cusack   +4 more
wiley   +1 more source

Laser fenestration of the dorsal pharyngeal recess does not correct experimentally induced dorsal nasopharyngeal collapse in horses

open access: yesVeterinary Surgery, Volume 55, Issue 1, Page 88-100, January 2026.
Abstract Objective To quantify the impact of experimentally induced dorsal nasopharyngeal collapse (NPC) on respiratory performance parameters and assess the efficacy of laser fenestration of the dorsal pharyngeal recess as a treatment option for experimentally induced NPC. Study design Experimental interventional study. Animals Six adult Standardbreds
Sharon Jeong   +3 more
wiley   +1 more source

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