Results 151 to 160 of about 4,459,628 (347)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Review of EIA decision-making with respect to the treatment of new information and natural justice/procedural fairness

open access: yes, 2006
This report presents a review of international and Australian practice of environmental impact assessment (EIA) with respect to the treatment of new information entering the process near or during the approval decision-making point.
Morrison-Saunders, A.
core  

Decision procedures for linear arithmetic

open access: yes, 2019
Nous introduisons dans cette thèse quelques procédures de décision nouvelles pour l'arithmétique linéaire adaptées à une utilisation dans le cadre de la résolution de contraintes modulo théories (SMT) ou d'outils de déduction automatique.1) CutSat++ est un calcul pour l'arithmétique linéaire sur les entiers qui intègre des techniques issues de la ...
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Leadership and Fairness: The State of the Art

open access: yes
Research in leadership effectiveness has paid less to the role of leader fairness than probably it should have. More recently, this has started to change.
Cremer, D. de   +2 more
core  

Procedural Rationality in the Decision-Making of Internationalizing SMEs

open access: yes, 2016
This paper contributes to the growing body of empirical work on how SME decision-makers decide to internationalize in two ways: first, it responds to recent calls for incorporating strategic decision-making literature into understanding SME ...
Hsieh, Linda   +13 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Procedural justice

open access: yes, 2007
Entry provides a concise description of procedural justice -the perceived fairness of organizational procedures in decision-making processes A conceptual overview, critical commentary and future directions provide the framework for this entry.\ud \ud The
Young, Angus
core  

Procedural Justice in Group Decision Support

open access: yes, 2019
This is a chapter in the Handbook of Group Decision and Negotiation, which is a Major Reference Work (MRW) produced by Springer.This chapter reports a case study that explicitly considers dimensions of procedural justice in the negotiation of new ...
Carreras, Ashley, Kaur, Parmjit
core   +1 more source

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