Results 241 to 250 of about 189,113 (324)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Arnold-Chiari malformation is associated with increased likelihood of a procedure in idiopathic intracranial hypertension. [PDF]

Front Ophthalmol (Lausanne)
Ma J, Nguyen P, Lee J, Athukorala C, Reid K.   +4 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Optimization of Outflow-Tract Ventricular Arrhythmia Ablation Using a Universal Right Ventricle Model. [PDF]

J Cardiovasc Dev Dis
Szkoła K, Zarębski Ł, Turek P, Futyma M, Wiśniowski Ł, Futyma P.   +5 more
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Triglyceride-glucose index predicts early, short-term, and long-term mortality after transcatheter aortic valve replacement. [PDF]

Am Heart J Plus
Abu Khadija H, Najajra D, Masu'd M, Abu Hamdeh N, Ayyad O, Mahamid A, Bagan M, Abdullah A, Alkrinawi J, Zayed A, Darwish A, Enairat ALE, Kirzhner A, Schiller T, Alnees M.   +14 more
europepmc   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Procedural Level Generation with Diffusion Models from a Single Example

Shiqi Dai, Xuanyu Zhu, Naiqi Li, Tao Dai, Zhi Wang   +4 more
openalex   +2 more sources

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Revolutionizing Pediatric Endodontics: A Two-Decade Narrative on the Evolution, Efficiency, and Future of Pediatric Rotary Systems. [PDF]

Cureus
Singh A, Saha S, Dhinsa K, Navit S, Jaiswal K, Kalita M, Sarkar A, Pandey S, Gupta S.   +8 more
europepmc   +1 more source