Results 141 to 150 of about 13,380 (311)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Learning to program : a cognitive model for an ITS [PDF]
Programming is a complex skill acquired only after considerable practice. This paper outlines a hierarchical cognitive model of problem solving and programming.
Craig, Iain D., Thomas, Robert F.
core
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
XScript - Shell Programming with X
Shell programs are still widely used in Unix systems. This paper reports on a system that supplies a number of X Window applications that are suitable for use in shell scripts.
Programming X, Jan Newmarch
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Programming Microcontrollers in C
C is a function based language. You will see that C uses far morefunctions than other procedural languages. In fact, any C program itselfis merely a function. This function has a name declared by thelanguage.
Sickle, Ted Van
core
On Tree Pattern Matching by Pushdown Automata
Tree pattern matching is an important operation in Computer Science on which a number of tasks such as mechanical theorem proving, term-rewriting, symbolic computation and non-procedural programming languages are based on.
T. Flouri
doaj
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Procedural programming in database
Thesis deals with verification of concept of performing calculations inside database. Describes PostgreSQL database, its features and procedural language PL/pgSQL.
Nimrichter, Adam
core +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source

