Results 61 to 70 of about 13,380 (311)

Awkward Just-In-Time (JIT) Compilation: A Developer’s Experience [PDF]

EPJ Web of Conferences
Awkward Array is a library for performing NumPy-like computations on nested, variable-sized data, enabling array-oriented programming on arbitrary data structures in Python.
Osborne Ianna, Pivarski Jim, Ifrim Ioana, Hollands Angus, Schreiner Henry   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

ECOLE: a pedagogical environment for non procedural languages

Journal of Computer Science and Technology, 2007
The work described in this paper is related to three areas in the programming world : logic, functional and object programming. The main objective is essentially pedagogical since it is question here to make a synthesis on non procedural languages.
D. E. Zegour, W. K. Hidouci
doaj  

An Experimental Study to Evaluate the Impact of the Programming Paradigm in the Testing Activity

CLEI Electronic Journal, 2012
Several techniques and criteria are available to help conducting testing activity. The choice for one of them depends on different aspects, such as the time restrictions, ef- fectiveness of the testing criteria or the features of the program under test ...
Simone de Rocio Senger de Souza, Marllos Paiva Prado, Ellen Francine Barbosa, José Carlos Maldonado   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Object-Oriented Programming in Bulgarian Universities' Informatics and Computer Science Curricula

Informatics in Education, 2008
Teaching object-oriented programming (OOP) is related to many difficulties. There is no single view on their causes among the university teachers. The results of applying various methods of teaching - with early or late introduction of the objects, are ...
Ivaylo DONCHEV, Emilia TODOROVA
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Research on the practice of collaborative teaching mode between python programming course and ideological and political education [PDF]

ITM Web of Conferences
In response to the problem that ideological and political education cannot be well integrated into programming courses, an exploration was conducted on the ideological and political education teaching mode of the "Python Programming" course. Firstly, the
Gu Cuihong, Wang Mengxia, Wang Qun
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source