Results 211 to 220 of about 10,637,308 (285)

Predictors of Procedural Pain in Office Hysteroscopy. [PDF]

Med Sci Monit
Şahin B, Akça A.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Is preoperative emergency department utilization associated with postoperative healthcare utilization after total joint arthroplasty? A social vulnerability index based analysis. [PDF]

PLoS One
Burke JF, Vennitti CE, Novicoff WM, Oley M, Browne JA, Duensing IM.   +5 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Fluoroscopy-minimization strategy for catheter ablation of Supraventricular Tachycardia by wOmen OPerators: the STOOP Multicentre Registry. [PDF]

Europace
Poggi S, Giaccardi M, Cipolletta L, Jordan A, Teres C, Serdoz LV, Buia V, Ghiglieno C, Meynet I, Soria LV, Nesti M, Garibaldi S, Casella M, Adelino R, Iuliano A, Torri F, Agresta A, Caruso R, Troisi F, De Regibus V, Mangiafico V, Strisciuglio T.   +21 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Report on the Wrocław Seminar in Criminal Procedure "The Concept, Position and Significance of Truth in Criminal Procedure" (Wroclaw, 11 March 2013)

Wroclaw Review of Law, Administration and Economics, 2013
Kremens Karolina
doaj   +1 more source

Clinical Application of Turnover Lengthening of the Palmaris Longus Tendon in Modified Camitz Opponensplasty for Severe Carpal Tunnel Syndrome. [PDF]

Hand (N Y)
Inami K, Hirase Y, Usami S, Kawahara S, Takemitsu M.   +4 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

ECTR With Tourniquet and Local Anesthesia Only: Efficiency and Patient Satisfaction. [PDF]

Hand (N Y)
Zilinskas K, Bakshi R, Clemmons K, Zilinskas MB, Hoey A, Tavana ML.   +5 more
europepmc   +1 more source