Results 101 to 110 of about 13,025,101 (327)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The Influence of Age and Experience on Safety Climate Perceptions Among Healthcare Staff in Operating, Interventional Radiology, and Hybrid Operating Rooms: A Cross-Sectional Study

open access: yesJournal of Multidisciplinary Healthcare
Johanna Rhodin,1,2 Sofia Erestam,1,2 May Bazzi,1,2 Jenny Milton,2,3 Sofia Strömberg,4,5 Monica Pettersson2 1Department of Hybrid and Interventional Procedures, Vascular Unit, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Institute of Health and ...
Rhodin J   +5 more
doaj  

Future Quality in the Emergent European Higher Education Area Involves the Use of Informatics

open access: yesInformatics in Education, 2008
In this paper an agreed set of standards, procedures and guidelines on quality assurance for the emergent European Higher Education Area is presented. If this set is implemented, the procedures for the recognition of qualifications will be strengthened ...
Javier BILBAO   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Peripheral Lymphadenopathy: Approach and Diagnostic Tools

open access: yesIranian Journal of Medical Sciences, 2014
Peripheral lymph nodes, located deep in the subcutaneous tissue, clean antigens from the extracellular fluid. Generally, a normal sized lymph node is less than one cm in diameter. Peripheral lymphadenopathy (LAP) is frequently due to a local or systemic,
Shahrzad Mohseni   +5 more
doaj  

UltRAP‐Net: Reverse Approximation of Tissue Properties in Ultrasound Imaging

open access: yesAdvanced Intelligent Systems
Medical ultrasound (US) has been widely used in clinical practices due to its merits of being low cost, real time, and radiation free. However, its capability to reveal the underlying tissue properties remains underexplored.
Yingqi Li   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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