Results 131 to 140 of about 5,817,656 (249)

Current and Future Liquid Argon Neutrino Experiments

, 2013
The liquid argon time projection chamber (LArTPC) detector technology provides an opportunity for precision neutrino oscillation measurements, neutrino cross section measurements, and searches for rare processes, such as SuperNova neutrino detection ...
Karagiorgi, Georgia
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

MesonNet 2013 International Workshop. Mini-proceedings

, 2013
The mini-proceedings of the MesonNet 2013 International Workshop held in Prague from June 17th to 19th, 2013, are presented. MesonNet is a research network within EU HadronPhysics3 project (1/2012 -- 12/2014).
Amaryan, M. J., Balkestahl, L. Caldeira, Balwierz-Pytko, I., Bashkanov, M., Benayoun, M., Bergmann, F., Bijnens, J., Clement, H., Colangelo, G., Daub, J., Eidelman, S., Fang, S., Gajos, A., Giovannella, S., Goudzovski, E., Grzonka, D., Gullström, C. O., Gumberidze, M., Heijkenskjöld, L., Hejny, V., Hoferichter, M., Husek, T., Ikeno, N., Ivashyn, S., Johansson, T., Kadavý, T., Kampf, K., Kolesár, M., Kupsc, A., Lang, M., Longhi, I. Prado, Lorenz, M., Lutz, M. F. M., Machner, H., Masjuan, P., Metag, V., Moussallam, B., Nagahiro, H., Nanova, M., Niecknig, F., Papenbrock, M., Pettersson, J., Peña, M. T., Prencipe, E., Przygoda, W., Redmer, C. F., Sarra, I., Sawant, S., Schneider, S. P., Shwartz, B., Skurzok, M., Tanaka, Y. K., Terschlüsen, C., Unverzagt, M., Yamagata-Sekihara, J., Zdráhal, M., Zétényi, M.   +56 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Scientific proceedings [PDF]

Archives of Disease in Childhood, 1983
openaire   +2 more sources

Higgs boson search at ATLAS

, 2012
The status of the ATLAS Higgs boson search using about 5 fb^-1 of data recorded in 2011 is summarized. Proceedings from Physics at the LHC 2012 (Vancouver).Comment: 6 pages.
Snyder, Scott
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Societies' Proceedings [PDF]

The Journal of Laryngology & Otology, 1922
openaire   +1 more source