Results 221 to 230 of about 6,083,333 (340)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Operationalising Article 13 of the Convention on the Rights of Persons with Disabilities the role of assistive technology in ensuring access to justice. [PDF]

Front Rehabil Sci
McVeigh J.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Correction for Tian et al., DNA polymerase delta governs parental histone transfer to DNA replication lagging strand. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Administrative Proceedings as a Way to Protect Subjective Public Rights and Legitimate Interests [PDF]

Olga S. Rogacheva
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Characterization of cases and analysis of First-instance Judgments in Ethical Proceedings at the Regional Council of Veterinary Medicine of the State of São Paulo. [PDF]

Braz J Vet Med
Ruiz RT, Bosch RV, Stringari S, Ruiz JLM, Maiorka PC.   +4 more
europepmc   +1 more source

Electrophysiological effects of bunaphtine on guinea pig myocardium [proceedings].

, 1979
Juan Tamargo
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The Politics of Interdictive Jurisprudence: Interrogative Practices and Psychological Evaluations (Gemütszustandsuntersuchungen) in the Adjudication of Civil Interdiction Cases before Berlin's District Courts (1877-1914). [PDF]

NTM
Engstrom EJ.
europepmc   +1 more source