Results 231 to 240 of about 5,909,358 (337)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Correction for Bawa et al., Prevalence of monogamy at the level of flowers in plants. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +1 more source
Proceedings of the 2025 NASSi Annual Meeting. [PDF]
N Am Spine Soc JHsieh PC +7 more
europepmc +1 more source
Report on the proceedings of the United States expedition to Lady Franklin Bay, Grinnell Land
, 1888 A. W. Greely, A. W. Greely
openalex +2 more sources
Exam‐level analysis of lecture capture viewing and student exam performance
FEBS Open Bio, EarlyView.This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Correction for Bonetti et al., Decoding the elite soccer player's psychological profile. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +1 more source