Results 71 to 80 of about 17,633,707 (261)

COMPUTATIONAL EXPERIMENT AND ITS GRAPHICAL MODELING

Ìнформаційні технології в освіті, 2011
Article explains to the reader what “computational experiment” is and gives basic definitions of this notion. This article has a practical application because tells how and in what condition is better to use computational experiment and graphical ...
M. Dubovik
doaj  

Academic citizenship, together: Prioritising care and reflexivity in scholarly life

JPHE
This essay explores dimensions of academic citizenship relating to collegiality and collectivity within academia. Building on notions of reflexivity and care, and from a starting point that highlights some of the problems of the conditions and nature of
Bao-Chau Pham, Kathleen Gregory, Sarah Davies, Andrea Schikowitz, Esther Dessewffy, Elaine Goldberg , Nora Ederer, Ariadne Avkıran, Constantin Holmer   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Les démarches de projet d’architecture et de paysage comme recherche

Projets de Paysage, 2009
Based on an experience of link between research and project, the author enumerates several important phases enabling to articulating them in the history.
Laurence Kimmel
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On the question of the mussel meat level shrinking at drying

Новые технологии, 2017
The article presents research in the field of drying mussel meat. In the course of the studies, the value of shrinkage coefficient for mussel meat is determined, which affects technological parameters of the drying process.
J. V. Karnaushenko
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Pre-Silicon Accurate SPICE Modeling of Trench MOSFETs via Advanced TCAD Simulations and Dynamic Validation

Micromachines
This work presents a novel and fully virtual flow for extracting the SPICE model of a power MOSFET, starting exclusively from TCAD simulations. Unlike traditional approaches that rely on experimental silicon data, our methodology enables designers to ...
Ammar Tariq, Giovanni Minardi, Valeria Cinnera Martino, Enza Fazio, Salvatore Rinaudo, Giuseppe Privitera, Fortunato Neri, Carmelo Corsaro   +7 more
doaj   +1 more source

Scalable process discovery and conformance checking [PDF]

, 2018
Considerable amounts of data, including process events, are collected and stored by organisations nowadays. Discovering a process model from such event data and verification of the quality of discovered models are important steps in process mining.
Aalst, WMP Wil van der, Fahland, D.; id_orcid, van der Aalst, W. M. P., Leemans, S. J. J., Leemans, SJJ Sander, Fahland, D Dirk, Fahland, D., Leemans, S.J.J., van der Aalst, W.M.P.   +8 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source