Results 101 to 110 of about 1,405,702 (265)
π-EconomyThe article provides a comprehensive analysis of the evolution of strategic paradigms, covering traditional approaches and modern methods of strategic management.
Baranovskiy Vladislav
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Integrating environmental assessment in the assembly line design process [PDF]
, 2013 This study focuses on including the environmental assessment of a process in its design. Two improvement targets can be considered to optimize the environmental efficiency of a production phase: a cleaner process, and the optimization of the assembly of ...
BOUTELLIER, Cedric +3 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015 The features of the realization of the process approach in quality management systems of educational institutions are presented at the article. The problems of the creating effective quality management system based on higher education institutions are ...
Vladimir A. Ivanov +1 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Modern methods of management of clinical and diagnostic processes
Ученые записки Российской академии предпринимательстваIn the context of the rapid development of medical technologies and the increasing burden on the healthcare system, the optimization of management of clinical and diagnostic processes is of particular and paramount importance. This article is devoted to
P. V. Abramov
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Effect of A Process Approach Using Report Writing Frame on Students’ Writing Achievement
IJET (Indonesian Journal of English Teaching), 2017 This study is aimed at investigating the effect of process approach using Report Writing Frame on students’ writing achievement. The design of this study was quasi-experimental design.
Khoiriyatul Hariro
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Process support for evolving active architectures
, 2003 This work is supported by the EC Framework V project ArchWare (IST-001-32360), and the UK Engineering and Physical Sciences Research Council (EPSRC) under grants GR/R51872 (Reflective Application Framework for Distributed Architectures) and GR/R67743 (my
Graham N. C. Kirby +35 more
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