Results 51 to 60 of about 1,405,702 (265)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Towards a pivotal-based approach for business process alignment. [PDF]
, 2011 This article focuses on business process engineering, especially on alignment between business analysis and implementation. Through a business process management approach, different transformations interfere with process models in order to make them ...
Le Lann, Jean-Marc +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Approaches to Biosimulation of Cellular Processes [PDF]
Journal of Biological Physics, 2006 Modelling and simulation are at the heart of the rapidly developing field of systems biology. This paper reviews various types of models, simulation methods, and theoretical approaches that are presently being used in the quantitative description of cellular processes.
Bruggeman, F.J., Westerhoff, H.V.
openaire +3 more sources
Product-process interface for effective product design and manufacturing in a DFM approach [PDF]
, 2009 This research work is partly supported by SNECMA enterprise. It makes part of the MAIA 8 projectIn order to tackle a continuous improvement of virtual engineering, product modelling has to integrate always more knowledge that refer to every decision ...
El Gueder, Jawhar +4 more
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
MANAGEMENT ASPECT OF THE PROBLEM OF NARCOTIC DRUGS USE
Фармакоэкономика, 2016 The use of narcotic drugs in healthcare system nowadays is characterized by lawful aspects prevalence over medical, bioethics, economic and social aspects.
S. Yu. Soboleva +2 more
doaj +1 more source
Management of cross-functional processes in culture institution [PDF]
Омский научный вестник: Серия "Общество. История. Современность", 2019 The article substantiates approach to process-based management as a key factor of market stability of culture institution. The basic principles of process-based management of culture institution such as allocation and description of crossfunctional ...
E. G. Khodzhayan
doaj +1 more source
Simplifying mined process models : an approach based on unfoldings
, 2011 Process models discovered using process mining tend to be complex and have problems balancing between overfitting and underfitting. Overfitting models are not general enough while underfitting models allow for too much behavior.
Toumani, F. +4 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source