By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Autotrophic nitrogen removal for decentralized treatment of ammonia-rich industrial textile wastewater: process assessment, stabilization and modelling. [PDF]
Visigalli S +11 more
europepmc +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Utilization Patterns and Optimization Suggestions for Wildlife Passages in Xinjiang Nature Reserves
The expansion of linear infrastructure presents a significant threat to biodiversity, emphasizing the urgent need for regional studies on spatial variations and comprehensive multispecies research.
Mengdi Fu +5 more
doaj +1 more source
A lightweight inductive method for process assessment based on frequent feedback: A study in a micro software company [PDF]
Software process assessment is the most important phase in process improvement projects since it enables identification of all process issues that need to be improved.
Stojanov Željko +2 more
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
How can we best measure fundamental movement skills? [PDF]
The assessment of movement skill is a critical component of many disciplines and professions. In particular, the effectiveness of movement programs hinges on accurate information about the skill level of participants.
Hands, Beth P
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Research in software allocation for advanced manned mission communications and tracking systems [PDF]
An assessment of the planned processing hardware and software/firmware for the Communications and Tracking System of the Space Station Freedom (SSF) was performed.
Kusmanoff, Antone +2 more
core +1 more source

