Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Mapping the path to reform: a qualitative study of stakeholder expectations for managerial assessment centers in Iran's health system. [PDF]
BMC Health Serv ResNaghshi M, Janati A, Khodayari-Zarnaq R.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Fossil-Free Polyethylene and Polypropylene Production via CCU and Biomass Pathways: A Harmonized Techno-Economic Assessment. [PDF]
ACS OmegaDing S +4 more
europepmc +1 more source
Enhancing home care nursing in the Netherlands: how can organisations facilitate the improvement of needs assessments in home care nursing? A focus group study. [PDF]
BMC Health Serv ResSchwenke M +6 more
europepmc +1 more source
Access and Reimbursement for Artificial Intelligence in Radiology: A Korean Perspective. [PDF]
Korean J RadiolLee CW.
europepmc +1 more source
Evidence-based nursing interventions in hepatocellular carcinoma care. [PDF]
Discov OncolWang D, Zhang Y, Wang Y.
europepmc +1 more source