Results 151 to 160 of about 588,383 (305)

Process Capability Analysis for Processes with Dependent Characteristics

open access: yes, 2013
One of the most important tools of statistical quality control is a process capability analysis. In order to measure process capability the most used are indices constructed for one-dimensional characteristic of production process.
Szerszunowicz, Małgorzata
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A study of process capability index using Bayesian approach under different prior

open access: yes, 2010
碩士隨著全球化的競爭激烈,以及生活水準的提高所帶來消費者對於產品的品質有更進一步的認識與要求的。因此,生產者必須更重視品質管理,以致於能達到或者超過消費者的需求,以提高與同行的競爭力。由於製程能力指標能夠客觀的表現出製程是否有能力製造出符合消費者所需的產品品質。近幾年來,製程能力指標發展逐漸成熟常被製造業品管上廣大的運用。目前最常使用的製程能力指標 、 、 及 等,而本研究的目的在於針對Chan et al.(1988)等學者所提出的製程能力指標 來進行信賴區間長度的估計 ...
曾國裕; Tzeng, Guo-yu
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Optimization of Bakery Products Manufacturing through Process Capability Analysis

open access: yes, 2011
Process capability analysis includes a set of analytic tools that allow comparing the real variability of a parameter, measured during a process, with the theoretical variability of the same parameter. This work has two aims.
VIGNALI, Giuseppe, BOTTANI, Eleonora
core  

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