Results 221 to 230 of about 12,380,713 (296)

Affective Computing in Serious Games for Physical Rehabilitation: Scoping Review. [PDF]

JMIR Rehabil Assist Technol
Beristain-Colorado MDP, Batres-Mendoza P, Guerra-Hernández EI, Cano-Pérez JL, Perezcampos-Mayoral C, Vargas-Treviño M, Gutiérrez-Gutiérrez J, Ambros-Antemate JF.   +7 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Advanced Electronic Packaging Technologies: A Comparative Review of Architectures, Applications, Reliability. [PDF]

Micromachines (Basel)
Huang Y, Wang D, Li Q, Pan Z.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Amplification of computational power by the multiplication of bacteria exploring microfluidic networks encoding mathematical problems. [PDF]

Microsyst Nanoeng
Sudalaiyadum Perumal A, van Delft FCMJM, Ippoliti G, Kašpar O, Tokárová V, Nayak M, Cho M, Li J, van Langen-Suurling A, de Boer C, Dirne F, Nicolau DV, Nicolau DV.   +12 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Sustainability-Focused Crypto Protocols Design Methodology for Sensors and IoT with the Deployment of LLMs. [PDF]

Sensors (Basel)
Trček D.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

High-precision hyperdimensional computing enabled by in-memory computing using high-polarization ferroelectric Hf_0.5Zr_0.5O₂ capacitors. [PDF]

Microsyst Nanoeng
Paasio E, Thomann S, Anu A, Li X, Ranta R, Srivari P, Muhammad S, Mazumder S, Mariam J, Padovani A, Amrouch H, Thareja G, Majumdar S.   +12 more
europepmc   +1 more source