Results 281 to 290 of about 22,284,815 (342)

A multi-GPU enabled solver in Kronecker product form for multiphysics problems. [PDF]

Sci Rep
Ma W, Zhao S, Le X, Yuan W.
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

SUANPAN: scalable photonic linear vector machine. [PDF]

Light Sci Appl
Yang Z, Li C, Ran Y, Li Y, Feng X, Cui K, Liu F, Sun H, Zhang W, Ye Y, Qiao F, Wang J, Ning CZ, Chang-Hasnain CJ, Huang Y.   +14 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Hundred-layer photonic deep learning. [PDF]

Nat Commun
Zhou T, Jiang Y, Xu Z, Xue Z, Fang L.
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Data management for distributed computational workflows: An iRODS-based setup and its performance. [PDF]

PLoS One
Hayek M, Golasowski M, Hachinger S, García-Hernández RJ, Munke J, Lindner G, Slaninová K, Tunka P, Vondrák V, Kranzlmüller D, Martinovič J.   +10 more
europepmc   +1 more source

An efficient framework for scheduling security-critical tasks in resource-limited mobile edge computing using hybridized gold rush with golden jackal optimization strategy. [PDF]

MethodsX
Vhatkar K, Koparde S, Deshpande N, Kothari S, Patil S, Kale R, Nimkar Darokar M, Bagane P.   +7 more
europepmc   +1 more source

An overhead-reduced, efficient, fully analog neural-network computing hardware. [PDF]

Sci Adv
Ye J, Wang W, Shi C, Cui X, Qu W, Lin P, Yu X, Cheng R, Wu H, Chen B.   +9 more
europepmc   +1 more source

Blockchain-based cryptographic framework for secure data transmission in IoT edge environments using ECaps-Net. [PDF]

Sci Rep
Mohamed Meerasha I, Syed Masood JAI, P T, R AA.   +3 more
europepmc   +1 more source