Results 71 to 80 of about 115,883 (217)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Service Oriented Computing: A New Challenge for Process Algebras

, 2006
Service Oriented Computing is emerging as a reference model for a new class of distributed computing technologies such as Web Services and the Grid. We discuss three main aspects of Service Oriented Computing (loose coupling, communication latency, and ...
Bravetti, Mario, Zavattaro, Gianluigi
core   +1 more source

Computer processing

Arxiu d'Etnografia de Catalunya, 2016
The preceding pages have been devoted to the presentation of our sources of basic information: the data sent in by the authors themselves and the systematic analysis of different blocks of bibliographic information proper. Clearly, however, neither the data in the curricula we received, nor those we ourselves extracted from already published sources ...
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Special Issue on Service-Oriented Collaborative Computing and Applications [PDF]

, 2018
The papers in this special issue focus on the research and development of service-oriented collaborative computing technologies and their applications to the design of products, processes, systems and services in an industrial and social ...
Aalst, WMP Wil van der, Jianming Yong, Chao, Kuo-Ming, Fortino, Giancarlo, Yang, Y Yun, Yun Yang, Wil van der Aalst, Van Der Aalst, Wil, Shen, Weiming, Yang, Yun, Chao, Kuo Ming, Yong, Jianming, Giancarlo Fortino, Weiming Shen, Kuo-Ming Chao, Fortino, Giancarlo   +15 more
core   +1 more source

A computer-assisted admissions process

Academic Medicine, 1977
A computer-assisted admissions process has been implemented at the Ohio State University College of Medicine to systematize the procedures for managing a greatly increased volume of applications. The historical development, continuing research efforts, and computer support system for the process are discussed.
J H, Williams, R E, Pengov, L, Sachs, C B, Meleca, J S, Camiscioni   +4 more
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Serverless Computing and Cloud Function-based Applications [PDF]

, 2019
Serverless computing is a growing industry trend with corresponding rise in interest by scholars and tinkerers. Increasingly, open source and academic system prototypes are being proposed especially in relation with cloud, edge and fog computing among ...
Josef Spillner, Spillner, Josef
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Evolution of the CMS Computing Model towards Phase-2

, 2021
The success of the physics program of the Compact Muon Solenoid (CMS) experiment critically depends on the availability of sufficient computing resources to store, process, and analyze data efficiently.
CMS Offline Software, Computing
core