Results 221 to 230 of about 12,031,440 (347)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Quality management of head and neck patient treatments using statistical process control techniques. [PDF]

Phys Eng Sci Med
Sandford MJ, Steel JG, Goodworth JR, Lodge PJ.   +3 more
europepmc   +1 more source

Architectural design and managerial control: Lefebvre, Latour and the process of enrollment [PDF]

J.J. McArthur, Stephen Dunne, Sarah Ivory   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Out-of-Distribution Detection and Radiological Data Monitoring Using Statistical Process Control. [PDF]

J Imaging Inform Med
Zamzmi G, Venkatesh K, Nelson B, Prathapan S, Yi P, Sahiner B, Delfino JG.   +6 more
europepmc   +1 more source

The Desirability Index as an Instrument for Multivariate Process Control

, 2004
Heike Trautmann
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Enhancing Process Control and Quality in Amorphous Solid Dispersions Using In-Line UV-Vis Monitoring of L* as a Real-Time Response. [PDF]

Pharmaceutics
Bezerra M, Almeida J, de Castro M, Grootveld M, Schlindwein W.   +4 more
europepmc   +1 more source

Professional Standards As an Integral Part of the Process of Transformation of Internal Control and Audit

Irina F. Vetrova, Margarita V. Melnik
openalex   +2 more sources

Approach to building software collection, transmission and processing military intelligence in command control system

, 2015
P. P. Tckachyk, V. L. Zhyvchuk, Vasyl Lytvyn, Oksana Oborska   +3 more
openalex   +2 more sources