Results 231 to 240 of about 12,031,440 (347)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Potential Process Control Issues with Vasopressin. [PDF]

Contact Context
Isaacs JT, Almeter PJ, Hunter AN, Lyman TA, Zapata SP, Henderson BS, Larkin SA, Plymale AR, Long LM, Bossle MN, Bhaktawara SA, Warren MF, Lozier AM, Melson JD, Fraley SR, Relucio EHL, Felix MA, Reynolds JW, Naseman RW, Puerto DA, Lodder RA.   +20 more
europepmc   +1 more source

Approximate Policy Iteration for Robust Stochastic Control of Multiagent Markov Decision Processes

Feng Huang, Ming Cao, Long Wang
openalex   +2 more sources

Development of selective synthetic processes leading to fine chemicals. - Diastereofacial control in the nucleophilic addition to carbonyl compounds.

, 1989
Tamotsu Fujisawa, Yutaka Ukaji
openalex   +2 more sources

Advanced process control practices for continuous pharmaceutical twin-screw wet granulation [PDF]

, 2017
Nicolaï, Niels, Nopens, Ingmar, Gernaey, Krist V, De Beer, Thomas   +3 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

European standards for the grounding of criminal procedural decisions, what are the results of the court control process

Y. Y. Radzievsky
openalex   +2 more sources

Learner Control, Cognitive Processes, and Hypertext Learning Environments.

, 1995
Yonjoo Cho
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Analysis of door-to-needle time for thrombolysis in acute ischaemic stroke using statistical process control charts. [PDF]

BMJ Neurol Open
Grönroos M, Hällberg V, Helminen M, Koivistoinen T, Palomäki A.   +4 more
europepmc   +1 more source