Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Waste-derived mesoporous biochar for glycerol to glycerol carbonate upgrading: intensified process design and techno-economic analysis. [PDF]
RSC AdvSaetiao P, Kongrit N, Jitjamnong J.
europepmc +1 more source
Optimization Conditions of Malachite Green Adsorption onto Almond Shell Carbon Waste Using Process Design. [PDF]
Molecules, 2023 Chouli F +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Optimized Milling Approaches for Scalable Production of Ritonavir Nanocrystals: from Process Design to Bioperformance Evaluation. [PDF]
ACS Omegada Cunha Chaves MH +6 more
europepmc +1 more source
Process Design and Parameters Interaction in Material Extrusion 3D Printing: A Review. [PDF]
Polymers (Basel), 2023 Bouzaglou O, Golan O, Lachman N.
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Additive Manufacturing of Aerospace Composites: A Critical Review of the Material-Process-Design Interplay and Prospects for Application. [PDF]
Materials (Basel)Shen C, Guo Y, Shen Z, Yan F, Zhong N.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Machine Learning-Driven Pore-Scale Network Model Coupling Reaction Kinetics and Interparticle Transport for Catalytic Process Design. [PDF]
Adv Sci (Weinh)Qu ML +10 more
europepmc +1 more source