Results 121 to 130 of about 23,404,019 (398)

Enhancing the OPEN Process Framework with Service-Oriented Method Fragments [PDF]

open access: yesSoftware and Systems Modeling 13.1 (2014) 361-390, 2020
Service-orientation is a promising paradigm that enables the engineering of large-scale distributed software systems using rigorous software development processes. The existing problem is that every service-oriented software development project often requires a customized development process that provides specific service-oriented software engineering ...
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Modelling and managing reliability growth during the engineering design process [PDF]

open access: yes, 2010
[This is a keynote speech presented at the 2nd International Conference on Design Engineering and Science, discussing modelling and managing reliability growth during the engineering process.] Reliability is vital for safe and efficient operation of ...
Quigley, J.L., Walls, Lesley
core  

Agile Software Engineering and Systems Engineering at SKA Scale [PDF]

open access: yesarXiv, 2017
Systems Engineering (SE) is the set of processes and documentation required for successfully realising large-scale engineering projects, but the classical approach is not a good fit for software-intensive projects, especially when the needs of the different stakeholders are not fully known from the beginning, and requirement priorities might change ...
arxiv  

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Editorial: Microorganism and process engineering for biosynthesis. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Qi X, Cui J, Mofijur M, Zabed HM.
europepmc   +1 more source

Understanding requirements engineering process: a challenge for practice and education [PDF]

open access: yes, 2005
Reviews of the state of the professional practice in Requirements Engineering (RE) stress that the RE process is both complex and hard to describe, and suggest there is a significant difference between competent and "approved" practice.
Armarego, J., Nguyen, L., Swatman, P.
core   +1 more source

Feature Engineering for Predictive Modeling using Reinforcement Learning

open access: yes, 2017
Feature engineering is a crucial step in the process of predictive modeling. It involves the transformation of given feature space, typically using mathematical functions, with the objective of reducing the modeling error for a given target.
Khurana, Udayan   +2 more
core   +1 more source

RPSE: Reification as Paradigm of Software Engineering [PDF]

open access: yesarXiv, 2018
The paper introduces RPSE, Reification as a Paradigm of Software Engineering, and enumerates the most important theoretical and practical problems of the development and application of this paradigm. Main thesis: Software engineering is the reification (materialization of ideas) via the transformation of mental models into code executed on computers ...
arxiv  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

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