Results 181 to 190 of about 5,351,373 (348)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Enhanced Production of Antimicrobial Pyocyanin Using Electromagnetic Fields and Carbon Nanotubes

open access: yesNanotechnology, Science and Applications
Joanna Honselmann genannt Humme,1 Kamila Dubrowska,1 Dawid Sołoducha,1 Tomasz Borowski,1 Adrian Augustyniak,1,2 Rafał Rakoczy1,2 1Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West ...
Honselmann genannt Humme J   +5 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Process engineering of pH tolerant Ustilago cynodontis for efficient itaconic acid production. [PDF]

open access: yesMicrob Cell Fact, 2019
Hosseinpour Tehrani H   +4 more
europepmc   +1 more source

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