Results 51 to 60 of about 1,249,305 (259)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

USE OF NEURAL NETWORKS IN PROCESS ENGINEERING Thermodynamics, diffusion, and process control and simulation applications

CT&F Ciencia, Tecnología & Futuro, 1998
This article presents the current status of the use of Artificial Neural Networks (ANNs) in process engineering applications where common mathematical methods do not completely represent the behavior shown by experimental observations, results, and plant
F OTERO
doaj  

The improvement of maintenance service for traction networks equipment on the base of process approach

Nauka ta progres transportu, 2014
Purpose. The new methods development for improving the maintenance service for equipment of traction networks in order to increase its efficiency and quality. Methodology.
D. V. Mironov
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli

Microbial Cell Factories, 2023
Background Palifermin (trade name Kepivance®) is an amino-terminally truncated recombinant human keratinocyte growth factor 1 (KGF-1) with 140 residues that has been produced using Escherichia coli to prevent and treat oral mucositis following radiation ...
Young Su Kim, Hye-Jeong Lee, Gabriella Aphrodita Handoko, Jaehui Kim, Seong-Bo Kim, Minho Won, Jung-Ho Park, Jungoh Ahn   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Generative artificial intelligence in chemical engineering spans multiple scales

Frontiers in Chemical Engineering
Recent advances in generative artificial intelligence (GenAI), particularly large language models (LLMs), are profoundly impacting many fields. In chemical engineering, GenAI plays a pivotal role in the design, scale-up, and optimization of chemical and ...
Benjamin Decardi-Nelson, Benjamin Decardi-Nelson, Abdulelah S. Alshehri, Abdulelah S. Alshehri, Fengqi You, Fengqi You, Fengqi You   +6 more
doaj   +1 more source

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2

iScience, 2020
Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy, Yanming Wang, Nicole Pearcy, Martin Hayes, Edward Lester, Nigel P. Minton, Alex V. Conradie   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source