Results 211 to 220 of about 37,646,315 (377)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Evaluation of Springback and Post-Formed Mechanical Properties of DP800 Steel in Warm-Hat-Shaped Bending Process

Nurkan Karabulut, Nuri Şen, Tolgahan Civek   +2 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Understanding a Complex Intervention to Reduce Unplanned Hospitalizations From Nursing Homes: Process Evaluation of INTERCARE. [PDF]

Health Sci Rep
Zúñiga F, Kotkowski K, Guerbaai RA, Simon M, Serdaly C, Geest S, Zeller A, Kressig RW, Wellens NIH, Brunkert T.   +9 more
europepmc   +1 more source

Study and Economic Evaluation on the Process of Calorific Value Adjustment in the LNG Receiving Terminal [PDF]

, 2016
Shuting Wang, Kun Huang, Xiaoshang Wang, Ning Liao, Wencan Yan, Quanbin Pei, Baoding Xia   +6 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A process evaluation of an eHealth intervention to strengthen the circle of tuberculosis care in Shigatse, Tibet, China. [PDF]

PLOS Glob Public Health
Haldane V, Zhang Z, Yin T, Zhang B, Li Y, Pan Q, Dainty KN, Rea E, Pasang P, Hu J, Wei X.   +10 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

WhatsApp-Based Intervention for Diabetes Prevention and Care in Argentina: Implementation and Process Evaluation. [PDF]

JMIR Form Res
Nejamis A, Gutierrez L, López MV, Ciganda Cha AD, Mendoza Quispe O, Irazola V, Beratarrechea A.   +6 more
europepmc   +1 more source

Process Evaluation of a Community Garden at an Urban Outpatient Clinic

Journal of community health, 2017
B. Milliron, M. Vitolins, Elizabeth Gamble, Robert Jones, M. Chenault, J. Tooze   +5 more
semanticscholar   +1 more source