Results 211 to 220 of about 37,505,355 (338)

Natural Language Processing and Psychosis: On the Need for Comprehensive Psychometric Evaluation

, 2022
Alex S. Cohen, Zachary Rodriguez, Kiara K. Warren, Tovah Cowan, Michael D. Masucci, Ole Edvard Granrud, Terje B. Holmlund, Chelsea Chandler, Peter W. Foltz, Gregory P. Strauss   +9 more
openalex   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A process evaluation of an eHealth intervention to strengthen the circle of tuberculosis care in Shigatse, Tibet, China. [PDF]

PLOS Glob Public Health
Haldane V, Zhang Z, Yin T, Zhang B, Li Y, Pan Q, Dainty KN, Rea E, Pasang P, Hu J, Wei X.   +10 more
europepmc   +1 more source

FEATURES OF EVALUATION OF EVIDENCE IN CRIMINAL PROCESS.

, 2020
H. Ismoilov
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

WhatsApp-Based Intervention for Diabetes Prevention and Care in Argentina: Implementation and Process Evaluation. [PDF]

JMIR Form Res
Nejamis A, Gutierrez L, López MV, Ciganda Cha AD, Mendoza Quispe O, Irazola V, Beratarrechea A.   +6 more
europepmc   +1 more source

Process based synthesis to evaluate design flexibility in airport terminal layout [PDF]

, 2012
Sarah Shuchi, Robin Drogemuller
openalex  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Fermentation Process Evaluation of a Sustainable and Innovative Miso Made from Alternative Legumes. [PDF]

Foods
Santos R, Parente B, Mota M, Raymundo A, Prista C.   +4 more
europepmc   +1 more source