Results 251 to 260 of about 37,646,315 (377)

Protocol for the process evaluation of a randomised clinical trial of incremental-start versus conventional haemodialysis: the TwoPlus study. [PDF]

BMJ Open
Murea M, Foley KL, Gautam SC, Flythe JE, Raimann JG, Abdel-Rahman E, Awad AS, Niyyar VD, Kovach C, Roberts GV, Jefferson NM, Conway PT, Rosales LM, Woldemichael J, Sheikh HI, Raman G, Huml AM, Knicely DH, Hasan I, Makadia B, Lea J, Daugirdas JT, Gencerliler N, Divers J, Kotanko P, TwoPlus Research Consortium, Nwaozuru UC.   +26 more
europepmc   +1 more source

Learning agreement pilots : process evaluation [PDF]

, 2009
Maguire, Sue
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

'Better sleep, better wellbeing': Qualitative process evaluation of a hybrid, digital cognitive behavioural therapy programme for employees with sleep and emotion regulation problems. [PDF]

Br J Health Psychol
Hurley-Wallace A, Fletcher S, Moukhtarian TR, Patel K, Payne A, Jackson T, Toro C, Daly G, Russel S, Walasek L, Tang NKY, Meyer C.   +11 more
europepmc   +1 more source

HealtheSteps Process Evaluation

Medicine & Science in Sports & Exercise, 2018
Wendy Blunt, Dawn P. Gill, Brendan Riggin, Judith Belle Brown, Robert J. Petrella   +4 more
openaire   +2 more sources

Evaluating the influence of the compression ratio on the combustion process using methanol, gasoline, and methanol-gasoline blends

Ruobing Liu, Qi Cui, Hanyi Li, Haiyi Wang, Xiao Dong Chen, Jaehyun Jin, Jinping Liu, Feng Zhou   +7 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

From audit to action: nurses' experiences turning incident analyses into practice change-a qualitative process evaluation. [PDF]

BMC Nurs
Abdulqader AKA, Ali SI, Alamoudi FA, Shaban M.   +3 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Targeting men to improve maternal and child health and nutrition: A qualitative process evaluation of a mass media campaign in Tanzania's Lake Zone. [PDF]

PLoS One
Kezakubi D, Remes P, Atugonza V, Kayanda R, Clare A, Humphrey A, Murray J, Head R.   +7 more
europepmc   +1 more source