Results 261 to 270 of about 37,505,355 (338)

Improve your library : a self-evaluation process for primary schools [PDF]

, 2004

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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

De-implementation of low-value home-based nursing care: an effect and process evaluation. [PDF]

Implement Sci Commun
Cremers M, Schoonhoven L, van Bodegom-Vos L, Bleijenberg N, Witsiers C, van Dijk M, Ista E.   +6 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Process Evaluation of a Rapid Evidence Support System Assessment of Ireland's Department of Health - A Protocol. [PDF]

HRB Open Res
Tierney M, Whelan B, Burke NN, Creely C, Duffy T, Gill C, Horgan M, Lavis JN, Maguire T, O'Driscoll M, O'Neill J, Toomey E, Waddell K, Devane D.   +13 more
europepmc   +1 more source

Process evaluation of a practice nurse-led smoking cessation trial in Australian general practice: views of general practitioners and practice nurses.

Family Practice, 2015
E. Halcomb, J. Furler, Oshana Hermiz, I. Blackberry, Julie P. Smith, R. Richmond, N. Zwar   +6 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Gaps and opportunities in mental health support for young people: a process evaluation of a multi component intervention. [PDF]

Front Public Health
Oha JT, Bridge G, Flood C, Jenkins CL, Taylor-Page C, Sykes S, Wills J, York W, Callaghan P, Reavey P.   +9 more
europepmc   +1 more source

Process evaluation in randomised controlled trials of complex interventions

British medical journal, 2006
A. Oakley, V. Strange, C. Bonell, E. Allen, J. Stephenson   +4 more
semanticscholar   +1 more source

Activity agreement pilots : process evaluation [PDF]

, 2009
Maguire, Sue
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