Results 311 to 320 of about 37,505,355 (338)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The POETIC (PrOcess Evaluation of Trials In Critical care) Framework: A Structured Approach for Designing and Conducting Process Evaluations in Critical Care Trials. [PDF]

Crit Care Explor
Emerson LM, McAuley DF, Blackwood B, Clarke M.   +3 more
europepmc   +1 more source

A risk communication intervention aimed at enhancing help-seeking behavior and reducing stress symptoms in healthcare workers: a pilot study with a process evaluation. [PDF]

BMC Psychol
Emal LM, Tamminga SJ, Beumer A, Kezic S, Timmermans DR, Schaafsma FG, van der Molen HF.   +6 more
europepmc   +1 more source

Comparison of AHP and Fuzzy AHP for the Multi-Criteria Decision Making Processes with Linguistic Evaluations

, 2007
Aşkın Özdağoğlu, Güzin Özdağoğlu   +1 more
openalex   +1 more source

Saline nasal irrigation for acute sinusitis (SNIFS II): a randomised controlled pilot trial with nested process evaluation. [PDF]

BJGP Open
Venekamp RP, Ainsworth B, Thomas T, Stuart B, Slodkowska-Barabasz J, Mowbray F, Butler CC, Francis N, Richards-Hall S, Harnden A, Hay AD, Hopkins C, Moore M, Yardley L, Verheij TJ, Zhu S, Little P.   +16 more
europepmc   +1 more source

Assessing a penicillin allergy de-labelling implementation intervention in a UK hospital: a process evaluation reporting healthcare workers' experiences. [PDF]

JAC Antimicrob Resist
Powell N, Upton M, Kent B, Sandoe JAT, Tonkin-Crine S.   +4 more
europepmc   +1 more source

Process evaluation exploring implementation and delivery of a home-based extended exercise intervention for older people with frailty: the HERO trial.

Health Technol Assess
Hall AJ, Ziegler F, Prescott M, Goodwin VA, Hulme C, Farrin AJ, Thompson E, Forster A, Clegg A, Clarke D.   +9 more
europepmc   +1 more source