Results 191 to 200 of about 28,750,719 (342)

A Plan to Transform Primary and Community Care at Catalonia based on a process improvement methodology

, 2023
Coll MS, Manjón S, Salabert J, Pladevall C, Algar D, Benaque A, Soler J, de Echagüen AO.   +7 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Rational Utilization of Sugammadex Through Quantitative Twitch Monitoring: A Process Improvement Project at a Large Academic Medical Center. [PDF]

Cureus
Kowalsky M, Montejano J, Pattee J, Rist S, Fernandez-Bustamante A, Gilliland S, Weitzel N.   +6 more
europepmc   +1 more source

Effect of an Emergency Department Process Improvement Package on Suicide Prevention: The ED-SAFE 2 Cluster Randomized Clinical Trial.

JAMA Psychiatry, 2023
Boudreaux ED, Larkin C, Vallejo Sefair A, Ma Y, Li YF, Ibrahim AF, Zeger W, Brown GK, Pelletier L, Miller I, ED-SAFE 2 Investigators.   +10 more
europepmc   +1 more source

Establishing a Reference Procedure Length for Anterior Cervical Fusions: The Role for Standards in Surgical Process Improvement. [PDF]

Cureus, 2022
Bohl M, Kakarla UK, Chang SW, Sethi R, Farrokhi F, Leveque JC.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A plan to transform primary and community care at Catalonia based on a process improvement methodology. [PDF]

Prim Health Care Res Dev
Sales Coll M, Manjón S, Salabert J, Pladevall C, Algar D, Benaque A, Soler J, Ochoa de Echagüen Aguilar A.   +7 more
europepmc   +1 more source

Production of Gluconic Acid and Its Derivatives by Microbial Fermentation: Process Improvement Based on Integrated Routes. [PDF]

Front Bioeng Biotechnol, 2022
Ma Y, Li B, Zhang X, Wang C, Chen W.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

New insights on poly(<i>cis</i>-1,4-isoprene) rubber degradation through enzymatic kinetics and process improvement. [PDF]

Front Bioeng Biotechnol
Guajardo-Flores C, Rojas J, Baldera-Moreno Y, Adasme-Carreño F, Kasai D, Andler R.   +5 more
europepmc   +1 more source