Results 111 to 120 of about 30,391,045 (381)

Research on the Solution of Business Platform Security

open access: yesDianxin kexue, 2013
As an important support system,it is necessary for the telecommunication service platform to ensure the security of service system and the information data,and to try to avoid the negative effects brought by security events and economic loss.Based on the
Yanchun Wang, Hong Li
doaj  

Measuring performance in healthcare [PDF]

open access: yes, 2015
Hospitals invest in process management and process optimization from an organizational and patient perspective to increase efficiency and simultaneously the quality of their operations.
De Pourcq, Kaat   +2 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Life Cycle Assessment as a Tool of Environmental Safety in Car Recycling

open access: yesCommunications, 2008
Numerous and wide-ranging initiatives are being pursued all over the world today to help pass on a sound natural environment to future generations. Automotive production is one of Slovakian leading industries. Because of urgent priority on protecting the
Milan Majernik   +2 more
doaj   +1 more source

Management of processes of electrochemical dimensional processing

open access: yesIOP Conference Series: Materials Science and Engineering, 2017
© Published under licence by IOP Publishing Ltd. In different industries a lot high-precision parts are produced from hard-processed scarce materials. Forming such details can only be acting during non-contact processing, or a minimum of effort, and doable by the use, for example, of electro-chemical processing.
Z B Sadykov, A R Zakirova, I D Akhmetov
openaire   +3 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

THE TASKS OF IMPROVING THE MANAGEMENT SYSTEM OF PROGRAMMES AND PROJECTS IMPLEMENTATION IN MUNICIPAL ADMINISTRATIONS

open access: yesВестник университета, 2019
In the article problems of control systems of municipal authorities are considered. Problems of improvement of control systems of processes of implementation of programs and projects of development of business in administrations of municipal educations ...
R. Mamedov
doaj  

Reduction of waste production during juice processing with a simultaneous creation of the new type of added-value products

open access: yesEnvironmental Protection and Natural Resources, 2019
The paper presents a new method for the reduction of waste production during juice processing through the reformulation of cloudy juices by ultrafiltration (UF), resulting in simultaneous production of a new type of cloudy juice of reduced sugar content.
Samborska Katarzyna   +4 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

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