Results 111 to 120 of about 31,124,721 (333)
Research on the Solution of Business Platform Security
Dianxin kexue, 2013 As an important support system,it is necessary for the telecommunication service platform to ensure the security of service system and the information data,and to try to avoid the negative effects brought by security events and economic loss.Based on the
Yanchun Wang, Hong Li
doaj
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Life Cycle Assessment as a Tool of Environmental Safety in Car Recycling
Communications, 2008 Numerous and wide-ranging initiatives are being pursued all over the world today to help pass on a sound natural environment to future generations. Automotive production is one of Slovakian leading industries. Because of urgent priority on protecting the
Milan Majernik +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Environmental Protection and Natural Resources, 2019 The paper presents a new method for the reduction of waste production during juice processing through the reformulation of cloudy juices by ultrafiltration (UF), resulting in simultaneous production of a new type of cloudy juice of reduced sugar content.
Samborska Katarzyna +4 more
doaj +1 more source
Measuring performance in healthcare [PDF]
, 2015 Hospitals invest in process management and process optimization from an organizational and patient perspective to increase efficiency and simultaneously the quality of their operations.
De Pourcq, Kaat +2 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Knowledge Management: A Discovery Process [PDF]
, 2014 Getting strategic about how you organize and redistribute knowledge can help just about anyone achieve their goals more efficiently. We at The McKnight Foundation often find ourselves at the center of meaty, data-rich, analytic conversations.
Bernadette Christiansen +2 more
core
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source