Results 141 to 150 of about 31,124,721 (333)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Process Management of Intussusception in Children: A Retrospective Analysis in China. [PDF]

open access: yesPediatr Emerg Care, 2022
Sun Z, Song G, Lian D, Zhang Q, Dong L.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Present-day bureaucratic organization: managerial analysis

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2016
The article contains existing approaches to bureaucracy. There were defined 4 main management principles in bureaucratic organization on basis of Max Weber’s “rational bureaucracy” theory.
Dmitry S. Vitashov
doaj  

Heuristics for the Order-Picking Problem With Sequence-Dependent Constraints and a One-Directional Conveyor

open access: yesIEEE Access
Optimizing the logistic order-picking process in the distribution center depends on two closely related decisions: how to schedule the processing of orders by a limited number of employees and how to sequence the containers on the conveyor to be ...
Kateryna Czerniachowska, Marcin Hernes
doaj   +1 more source

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