Results 141 to 150 of about 25,622,262 (294)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Effects of reliability indicators on usage, acceptance and preference of predictive process management decision support systems. [PDF]

open access: yesQual User Exp, 2022
Fröhlich P   +6 more
europepmc   +1 more source

IT-enabled business process management [PDF]

open access: bronze, 2016
Wei Thoo Yue, Dongming Xu
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Inventions for better sharing information and integrating natural processes into the management of livestock grazing systems

open access: green, 2023
Jean-Baptiste Menassol   +5 more
openalex   +1 more source

Major Soilborne Pathogens of Field Processing Tomatoes and Management Strategies [PDF]

open access: gold, 2023
Minxiao Ma   +4 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Parenteral Nutrition Process Management for Newborn and Preterm Infants - A Preliminary Risk Analysis. [PDF]

open access: yesTher Clin Risk Manag, 2021
Sommer I   +5 more
europepmc   +1 more source

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