Results 171 to 180 of about 20,540,058 (264)

[Quantitative evaluation of radiotherapy plan in precise external beam radiotherapy process management for cervical cancer]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2023
Guo Y, Li T, Yang X, Qi Z, Chen L, Huang S.   +5 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Evaluating low-carbon construction of urban green spaces in China through a process management perspective. [PDF]

Sci Rep
Guo Y, Zhang Y, Xu X, Zhan P, Cao Z, Bai Y, Jiao L.   +6 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Status and prospects of low carbon development in offshore oil and gas industry

Youqicang pingjia yu kaifa
Under the “Dual Carbon” goals, achieving a green and low-carbon transformation in offshore oil and gas has become a significant challenge for enterprises.
CHEN Hongju, LIU Qiang, SUN Lili, YU Hang   +3 more
doaj  

Process management method in head and neck cancer patient care. [PDF]

Discov Oncol
De Felice F, Valentini V, Casarano F, Gaudino C, Di Gioia CRT, Tenore G, Della Monaca M, Cassoni A, Cirillo A, Corsi A, Botticelli A, Cerbelli B, Battisti A, Brauner E, Messineo D, De Virgilio A, Greco A, Santini D, Catalano C, Romeo U, Della Rocca C, Polimeni A, de Vincentiis M.   +22 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Effect of whole-process management based on planned behavior theory on postoperative recovery of acute appendicitis patients. [PDF]

World J Gastrointest Surg
Yin CL, Wu Y.
europepmc   +1 more source

[Utilizing Patient Navigation Model in the Whole-Process Management of Lung Cancer in the Context of Medical Consortiums in China: Insights and Reflections]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban, 2023
Tao W, Wen J, Li W.
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source