Results 131 to 140 of about 753,552 (216)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Process Mapping to Compare and Improve Management of Abnormal Cervical Cancer Screening Results in Two US Healthcare Systems within the PROSPR Consortium. [PDF]

Cancer Epidemiol Biomarkers Prev
Higashi RT, Quirk L, Kruse G, Chen PM, Dang TH, Haas JS, Atlas SJ, Feldman S, Kobrin SC, Lee SC, Santini N, Tiro JA.   +11 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Pathfinder studies: a novel tool for process mapping data-driven health research to build global research capacity. [PDF]

BMC Med Res Methodol
Uppal A, Kagoro F, Monteiro-Krebs L, Bueno FTC, Marques LP, Tessema SK, Amuasi J, Retford M, Baker B, Rumi M, Naheed A, Temfack E, Machado CV, Kiosia A, Kingpriest P, Lang T.   +15 more
europepmc   +1 more source

Systems thinking for health emergencies: use of process mapping during outbreak response. [PDF]

BMJ Glob Health, 2020
Durski KN, Naidoo D, Singaravelu S, Shah AA, Djingarey MH, Formenty P, Ihekweazu C, Banjura J, Kebela B, Yinka-Ogunleye A, Fall IS, Eteng W, Vandi M, Keimbe C, Abubakar A, Mohammed A, Williams DE, Lamunu M, Briand S, Changa Changa JC, Minkoulou E, Jernigan D, Lubambo D, Khalakdina A, Mamadu I, Talisuna A, Mbule Kadiobo A, Jambai A, Aylward B, Osterholm M.   +29 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Process Mapping to Support the Implementation of a Regional Strategy to Address the Opioid Epidemic. [PDF]

Healthcare (Basel)
Liu Y, Farr SL, Spertus JA, Olds DM, LaPierre TA, Renwick Hagle HN.   +5 more
europepmc   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Process Mapping of the Sol-Gel Transition in Acid-Initiated Sodium Silicate Solutions. [PDF]

Gels
Matinfar M, Nychka JA.
europepmc   +1 more source

Diagnosis and management of subcutaneous implantable cardioverter-defibrillator infections based on process mapping. [PDF]

Pacing Clin Electrophysiol, 2020
Baddour LM, Weiss R, Mark GE, El-Chami MF, Biffi M, Probst V, Lambiase PD, Miller MA, McClernon T, Hansen LK, Knight BP.   +10 more
europepmc   +1 more source