Results 151 to 160 of about 19,509,703 (356)
A framework for multifactor process mining [PDF]
, 2023 Luiz Fernando Puttow Southier +1 more
openalex
Dynamics of competitive interaction between two mining enterprises and one processing: existence and stability of the equilibrium point [PDF]
, 2020 Aleksandr Kirjanen +4 more
openalex +1 more source
Advanced Science, EarlyView.ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang +17 more
wiley +1 more source
Advanced Science, EarlyView.Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang +16 more
wiley +1 more source
ISPRS International Journal of Geo-InformationThis study examines the application of Geographic Information Systems (GIS) in tourism planning and sustainable destination management, using Gelnica, Slovakia, as a case study.
Marieta Šoltésová +3 more
doaj +1 more source
Object-Centric Process Mining Using Process Cubes [PDF]
, 2020 Anahita Farhang Ghahfarokhi +2 more
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Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source