Results 151 to 160 of about 21,359,437 (311)
Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity
Advanced Science, EarlyView.In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin +19 more
wiley +1 more source
Advanced Science, EarlyView.A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du +18 more
wiley +1 more source
ISPRS International Journal of Geo-InformationThis study examines the application of Geographic Information Systems (GIS) in tourism planning and sustainable destination management, using Gelnica, Slovakia, as a case study.
Marieta Šoltésová +3 more
doaj +1 more source
Bioinspired Microreactor for Iodide Adsorption and Photooxidation Recovery
Advanced Science, EarlyView.A bioinspired micro‐ionic‐reactor based on porous organic polymer (MIR‐POP) integrates rapid iodide capture with in situ photooxidative conversion, achieving record uptake capacity and high uptake efficiencies in simulated mining wastewater and natural brine. This bioinspired microreactor strategy offers a new avenue for sustainable iodine recovery and
Xuewen Cao +8 more
wiley +1 more source
Advanced Science, EarlyView.This study introduces a novel metamaterial absorber integrating water as a lossy medium with patterned indium tin oxide (ITO) films to achieve simultaneous optical transparency and ultra‐wideband electromagnetic absorption over 0.52‐40 GHz. It effectively overcomes the limitations of conventional opaque and bulky shielding materials, offering a ...
Xiaojun Huang +5 more
wiley +1 more source
Process Mining for Python (PM4Py): Bridging the Gap Between Process- and Data Science
, 2019 Process mining, i.e., a sub-field of data science focusing on the analysis of event data generated during the execution of (business) processes, has seen a tremendous change over the past two decades.
Berti, Alessandro +2 more
core
Advanced Science, EarlyView.Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma +15 more
wiley +1 more source
Advanced Science, EarlyView.Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu +9 more
wiley +1 more source
Selective Lithium Recovery via Photothermal Evaporation and Hydration‐Controlled Adsorption
Advanced Science, EarlyView.A bilayer Mo‐LDH@Sponge composite is developed to couple interfacial photothermal evaporation with hydration‐controlled lithium adsorption. Solar‐induced heating dynamically regulates Li+ hydration and transport, enabling selective lithium capture from saline water. This work provides mechanistic insight into photothermal–adsorption coupling for energy‐
Yanan Pan +4 more
wiley +1 more source