Results 181 to 190 of about 259,067 (305)

Process mining in healthcare: a tertiary study. [PDF]

open access: yesBMC Med Inform Decis Mak
Santos A, Leal GCL, Balancieri R.
europepmc   +1 more source

Applying process mining in health technology assessment. [PDF]

open access: yesHealth Technol (Berl), 2022
Dallagassa MR   +4 more
europepmc   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang   +9 more
wiley   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

open access: yesAdvanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng   +18 more
wiley   +1 more source

Analysis of Patients' Mobility Patterns: Insights From a Process Mining-Based Longitudinal Study. [PDF]

open access: yesInquiry
Yari Eili M   +6 more
europepmc   +1 more source

Sequence-oriented sensitive analysis for PM2.5 exposure and risk assessment using interactive process mining. [PDF]

open access: yesPLoS One, 2023
Illueca Fernández E   +4 more
europepmc   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

open access: yesAdvanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

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