Results 91 to 100 of about 4,086,367 (310)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Modeling and Carbon Emission Assessment of Novel Low-Carbon Smelting Process for Vanadium–Titanium Magnetite

open access: yesMetals
The iron and steel industry, as a major energy consumer, was critically required to enhance operational efficiency and reduce CO2 emissions. Conventional blast furnace processing of vanadium–titanium magnetite (VTM) in China had been associated with ...
Yun Huang, Jue Tang, Mansheng Chu
doaj   +1 more source

Process Models for Security Architectures [PDF]

open access: yesInformatică economică, 2006
This paper presents a model for an integrated security system, which can be implemented in any organization. It is based on security-specific standards and taxonomies as ISO 7498-2 and Common Criteria.
Floarea NASTASE, Radu CONSTANTINESCU
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Reliable Process Tracking Under Incomplete Event Logs Using Timed Genetic-Inductive Process Mining

open access: yesSystems
Process mining facilitates the discovery, conformance, and enhancement of business processes using event logs. However, incomplete event logs and the complexities of concurrent activities present significant challenges in achieving accurate process ...
Yutika Amelia Effendi, Minsoo Kim
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Performance Measurement in a Custom Production Process Model Using the Process Mining Approach: A Systematic Literature Review

open access: yesIEEE Access
This study aims to explore and develop a method for measuring supply chain performance influenced by customer demand in custom product production. The research method used is a systematic literature review, focusing on measuring key indicators and ...
Wawa Wikusna, Mustafid, Ferry Jie
doaj   +1 more source

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