Results 91 to 100 of about 25,160,792 (332)

Exploring Knowledge Engineering Strategies in Designing and Modelling a Road Traffic Accident Management Domain [PDF]

open access: yes, 2013
Formulating knowledge for use in AI Planning engines is currently something of an ad-hoc process, where the skills of knowledge engineers and the tools they use may significantly influence the quality of the resulting planning application.
Chrpa, Lukáš   +4 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Design project planning, monitoring and re-planning through process simulation [PDF]

open access: yes, 2009
Effective management of design schedules is a major concern in industry, since timely project delivery can have a significant influence on a company’s profitability.
Clarkson, PJ, Wynn, DC
core  

Industry views on water resources planning methods – prospects for change in England and Wales [PDF]

open access: yes, 2015
This paper describes a qualitative study of practitioner perspectives on regulated water resources planning practice in England and Wales. The study focuses on strengths and weaknesses of existing practice and the case for change towards a risk-based ...
Jeffrey, Paul J., Turner, Sean W. D.
core   +1 more source

Integrated process planning and scheduling using genetic algorithms

open access: yes, 2017
Original scientific paper Process planning and scheduling are two of the most important functions in any manufacturing system. Traditionally process planning and scheduling are considered as two separate functions.
I. Chaudhry, M. Usman
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Energy-aware integrated process planning and scheduling for job shops

open access: yesSustainable Manufacturing and Remanufacturing Management, 2015
Process planning that is based on environmental consciousness and energy-efficient scheduling currently plays a critical role in sustainable manufacturing processes.
Min Dai, D. Tang, Yuchun Xu, Weidong Li
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

CULTURE EFFECTS ON FORMAL PROCESS OF STRATEGIC PLANNING AND ORGANIZATION STRUCTURE [PDF]

open access: yes, 2001
The purpose of this essay is to describe how structure of the organization and its culture will affect the formal process of strategic planning and analysis.
Medianti, Nani
core  

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