Results 111 to 120 of about 11,437,873 (278)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Boosting projective methods for quantum process and detector tomography

Physical Review Research
We introduce two methods for quantum process and detector tomography. In the quantum process tomography method, we develop an analytical procedure for projecting the linear inversion estimation of a quantum channel onto the set of completely positive ...
Júlia Barberà-Rodríguez, Leonardo Zambrano, Antonio Acín, Donato Farina   +3 more
doaj   +1 more source

Global travel time tomography with 3-D reference models [PDF]

, 2007
In this study, a global high-resolution P-wave velocity model is obtained for the Earth's crust and mantle using travel time tomography. Improvements to previous models are achieved by incorporating additional data and advancing the method to use 3-D ...
Amaru, M.L., Mantle dynamics & theoretical geophysics, Seismic tomography with travel times   +2 more
core   +21 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Qualification and quantification of mixing processes of highly concentrated suspensions using electrical resistance tomography

, 2022
Art. O8-2In chemical and pharmaceutical industry as well as in wastewater treatment and biogas production, the qualification and quantification of mixing processes is a crucial requirement for process engineering and energetic optimization.
Rostalski, Kay, Deutschmann, Anne, Lomtscher, Annett, Kraume, Matthias, Jobst, Karin, Fogel, Stefan   +5 more
core   +1 more source

Perspective in data fusion between X-ray computed tomography and electrical capacitance tomography in an absorption column

, 2003
peer reviewedThis communication presents first results of an attempt to fuse the information obtained by X-ray tomography and by electrical capacitance tomography (ECT) on absorption columns.
Crine, Michel, Marchot, Pierre, Toye, Dominique, L’Homme, G.   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Coherence Tomography for Boreal Forest: Camparison with HUTSCAT Scatterometer Measurements [PDF]

, 2008
In this paper we report on X- and L-band polarization coherence tomography in boreal forest structure mapping. We take advantage of HUTSCAT ranging scatterometer measurements and compare E-SAR derived vertical structure profiles with measured vertical ...
Praks, Jaan, Papathanassiou, Konstantinos P., Kugler, Florian, Hallikainen, Martti   +3 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source