Results 211 to 220 of about 5,156,283 (297)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

CRUSADE project: Recycling technologies for ELV components to create a sustainable source of market grade materials for EU applications. [PDF]

Comput Struct Biotechnol J
Yakoumis I, Moschovi AM, Thoda O, Katsiapi A, Stamatopoulou P, Charitos A, Sandig-Predzymirska L, Wamunyu W, Adjapong S, Murru W, Veglio F, Zueva S, Passadoro M, Afantitis A, Mintis D, Tsoumanis A, Papadopoulou E, Paloumpis G, Theodoropoulos N, Zogali V, Xanthopoulos P, Gerolymatou L, Ataş DD, Durmuş Ö, Çelik M, Dönmez N, Güzeltepe B, Kama Y, Athanasakopoulos E, Babagiannou R, Baglio V, Vecchio CL, Gatto I, Sempere DA, Kromminga J, Santamarina E, Fernández A, Gieseking B, Prieto C, Abbate AV, Di Frangia M, Spreghini M, Di Muro F, Ferrara D, Brockerhoff L, Weber P, Lavoie P, Von Sivers D, Witzel F, Salehi F, Koc D, Nicol G, Costa R, Parussa F, Atia TA.   +54 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

A noninvasive strategy for multi-disease diagnosis via multi-sensor platform: integrative analysis of five years of exhaled breath-based diagnostics for seven diseases. [PDF]

Front Bioeng Biotechnol
Zompanti A, Pennazza G, Grasso S, Sabatini A, Di Loreto MV, Cenerini C, La Monica L, Vollero L, Incalzi RA, Pedone C, Finamore P, Scarlata S, De Vincentis A, Picardi A, Crucitti P, Longo F, Rocco G, Segreti A, Grigioni F, Santonico M.   +19 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Co-Designing a Primary Healthcare Intervention to Improve Diabetes Care in Mendoza, Argentina: A Qualitative Case Study. [PDF]

Health Expect
Roberti J, Mazzoni A, Guglielmino M, Silva C, Mazzaresi Y, Falaschi A, Hirschhorn LR, Parker JJ, García-Elorrio E.   +8 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation. [PDF]

Front Bioeng Biotechnol
Springuel P, Silva Couto P, Stibbs DJ, Szelwicki M, Frangleton A, Schmidberger T, George A, Slingsby F, Bevan N, Ahmad A, Legmann R, Dianat N, Ladi R, Hengst J, Rafiq QA.   +14 more
europepmc   +1 more source