Results 231 to 240 of about 17,750,200 (343)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Chemically Stable Atomic-Layer-Deposited Al2O3 Films for Processability
ACS Omega, 2017 Mikael Broas +4 more
doaj +1 more source
Sustainable Polyurethane Systems: Integrating Green Synthesis and Closed-Loop Recovery. [PDF]
Polymers (Basel)Kim TH, Kim HS, Lee SH.
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Solvent-Free Processing of i-P3HB Blends: Enhancing Processability and Mechanical Properties for Sustainable Applications. [PDF]
Polymers (Basel)Almustafa W +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Plasticizer-Enabled Solvent-Free Curing of Self-Healing Binder System for Energetic Materials. [PDF]
Polymers (Basel)Zhang M +9 more
europepmc +1 more source
Assessment of the processability of improved cassava varieties into a traditional food product (“baton” or “chikwangue”) in Cameroon [PDF]
, 2017 Bouniol, Alexandre +4 more
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source