Results 251 to 260 of about 7,512,539 (313)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mapping cross-domain drivers of Alzheimer's disease risk through integrated network analysis. [PDF]

open access: yesAlzheimers Dement
Cary GA   +10 more
europepmc   +1 more source

Aryl Hydrocarbon Receptor Signaling in Aging: A Key Modulator of Brain Homeostasis. [PDF]

open access: yesMol Neurobiol
Juárez-Solano H   +4 more
europepmc   +1 more source

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