Results 41 to 50 of about 2,359,967 (297)

Random rewards, fractional Brownian local times and stable self-similar processes [PDF]

, 2005
We describe a new class of self-similar symmetric $\alpha$-stable processes with stationary increments arising as a large time scale limit in a situation where many users are earning random rewards or incurring random costs.
Cohen, Serge, Samorodnitsky, Gennady
core   +3 more sources

Chunk boundaries disrupt dependency processing in an AG: Reconciling incremental processing and discrete sampling

PLOS ONE
Language is rooted in our ability to compose: We link words together, fusing their meanings. Links are not limited to neighboring words but often span intervening words. The ability to process these non-adjacent dependencies (NADs) conflicts with the brain’s sampling of speech: We consume speech in chunks that are limited in time, containing only a ...
Chia-Wen Lo, Lars Meyer
openaire   +4 more sources

Feller Processes: The Next Generation in Modeling. Brownian Motion, L\'evy Processes and Beyond [PDF]

, 2010
We present a simple construction method for Feller processes and a framework for the generation of sample paths of Feller processes. The construction is based on state space dependent mixing of L\'evy processes.
AN Kochubei, B Baeumer, B Böttcher, B Böttcher, B Böttcher, B Böttcher, B Böttcher, B Grigelionis, B Grigelionis, Björn Böttcher, D Reeves, D Stroock, DW Stroock, E Scalas, Enrico Scalas, FM Reynolds AM, H Janssen, J Jacod, JC Cox, K Sato, MM Meerschaert, N Ikeda, N Jacob, N Jacob, O Barndorff-Nielsen, P Chernoff, P Protter, PD Ditlevsen, R Bass, R Cont, R Schilling, RA Doney, VN Kolokoltsov, VY Gonchar, W Feller, W Hoh, WA Woyczyński, Y Zhang, ZM Ma   +38 more
core   +5 more sources

Pseudo-nonstationarity in the scaling exponents of finite-interval time series [PDF]

, 2009
The accurate estimation of scaling exponents is central in the observational study of scale-invariant phenomena. Natural systems unavoidably provide observations over restricted intervals; consequently, a stationary stochastic process (time series) can ...
Chapman, Sandra C., Kiyani, K., Watkins, Nicholas W.   +2 more
core   +3 more sources

Adaptive Planning for Markov Decision Processes with Uncertain Transition Models via Incremental Feature Dependency Discovery [PDF]

, 2012
Solving large scale sequential decision making problems without prior knowledge of the state transition model is a key problem in the planning literature. One approach to tackle this problem is to learn the state transition model online using limited observed measurements.
Geramifard, Alborz, Chowdhary, Girish, How, Jonathan P., Ure, Nazim Kemal   +3 more
openaire   +4 more sources

Incremental Query Processing on Big Data Streams [PDF]

, 2015
This paper addresses online query processing for large-scale, incremental data analysis on a distributed stream processing engine (DSPE). Our goal is to convert any SQL-like query to an incremental DSPE program automatically. In contrast to other approaches, we derive incremental programs that return accurate results, not approximate answers.
arxiv   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Large Deviations for High Minima of Gaussian Processes with Nonnegatively Correlated Increments [PDF]

Statistics and Probability Letters 206 (C). March 2024, 2021
In this article we prove large deviations principles for high minima of Gaussian processes with nonnegatively correlated increments on arbitrary intervals. Furthermore, we prove large deviations principles for the increments of such processes on intervals $[a,b]$ where $b-a$ is either less than the increment or twice the increment, assuming ...
arxiv  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source