Results 41 to 50 of about 43,734 (318)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Comparison of Three Smart Camera Architectures for Real-Time Machine Vision System
International Journal of Advanced Robotic Systems, 2013 This paper presents a machine vision system for real-time computation of distance and angle of a camera from a set of reference points located on a target board.
Abdul Waheed Malik +2 more
doaj +1 more source
GSPN-based Reliability Modeling and Analysis for Lock-step Processor System [PDF]
Jisuanji gongcheng, 2019 Aiming at the reliability modeling and analysis of lock-step self-monitoring processor system,based on the two-machine synchronous system,a lock-step self-monitoring processor system with error self-checking,fault location and failure repair function is ...
LI Lian, YANG Haotian
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
EURASIP Journal on Advances in Signal Processing, 2006 This paper presents an architecture that combines VLIW (very long instruction word) processing with the capability to introduce application-specific customized instructions and highly parallel combinational hardware functions for the acceleration of ...
Hoare Raymond R +6 more
doaj +1 more source
Processor architectures for ontogenesis [PDF]
Proceedings. 2004 NASA/DoD Conference on Evolvable Hardware, 2004., 2004 In this article we present the outline of a novel processor architecture aimed to the design of systems that more closely resemble, within the limitations imposed by the capabilities of conventional silicon, the general modus operandi of multicellular organisms.
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source