Results 61 to 70 of about 43,734 (318)

COMPONENT ARCHITECTURE OF WEB SERVICES ACCESS MANAGEMENT SYSTEM [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The component architecture of Web services access management system is presented. The executive kernel of the system is designed –processor of requests to web services.
A. M. Dergachev, A. A. Dergachev
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Speeding up the Discrete Cosine Transform Through Custom Operations and Fixed-Point Arithmetic

Journal of Innovative Science and Engineering
Digital signal processing applications are becoming increasingly important because modern systems work with much larger amounts of data than before.
Mustafa Alptekin Engin
doaj   +1 more source

Sensitivity Study on Availability of I&C Components Using Bayesian Network

Science and Technology of Nuclear Installations, 2013
The objective of this study is to find out the impact of instrumentation and control (I&C) components on the availability of I&C systems in terms of sensitivity analysis using Bayesian network.
Rahman Khalil Ur, Jinsoo Shin, Muhammad Zubair, Gyunyoung Heo, Hanseong Son   +4 more
doaj   +1 more source

Impact of Microarchitectural Differences of RISC-V Processor Cores on Soft Error Effects

IEEE Access, 2018
In this paper, we compare how radiation-induced soft errors affect the execution results of user-level applications on different processor cores that implement the same instruction set architecture (ISA).
Hyungmin Cho
doaj   +1 more source

Superconductor Processor Architecture

TEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan), 2021
Koji INOUE, Masamitsu TANAKA, Koki ISHIDA   +2 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Discrete Cosine Transform , Efficient processor design , Signal processing , Transport-Triggered Architecture , Application-specific processor design

Journal of Innovative Science and Engineering
This study examines the impact of hybrid layer thickness configurations on the mechanical properties and energy consumption of 3D-printed polylactic acid (PLA) parts produced via Fused Deposition Modeling (FDM). PLA specimens with various combinations of
Mesut Uysal
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source