Results 61 to 70 of about 18,777,208 (356)
A Taxonomy of Reconfigurable Single-/Multiprocessor Systems-on-Chip
International Journal of Reconfigurable Computing, 2009 Runtime adaptivity of hardware in processor architectures is a novel trend, which is under investigation in a variety of research labs all over the world.
Diana Göhringer +3 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Frontiers in Neuroscience, 2015 Implementing compact, low-power artificial neural processing systems with real-time on-line learning abilities is still an open challenge. In this paper we present a full-custom mixed-signal VLSI device with neuromorphic learning circuits that emulate ...
Ning Qiao +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Sensitivity Study on Availability of I&C Components Using Bayesian Network
Science and Technology of Nuclear Installations, 2013 The objective of this study is to find out the impact of instrumentation and control (I&C) components on the availability of I&C systems in terms of sensitivity analysis using Bayesian network.
Rahman Khalil Ur +4 more
doaj +1 more source
Impact of Microarchitectural Differences of RISC-V Processor Cores on Soft Error Effects
IEEE Access, 2018 In this paper, we compare how radiation-induced soft errors affect the execution results of user-level applications on different processor cores that implement the same instruction set architecture (ISA).
Hyungmin Cho
doaj +1 more source
ETRI Journal, 2020 The proposed AI processor architecture has high throughput for accelerating the neural network and reduces the external memory bandwidth required for processing the neural network.
Jinho Han, Minseok Choi, Youngsu Kwon
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source