Results 171 to 180 of about 592,784 (368)

The private finance initiative (PFI) and finance capital: A note on gaps in the "accountability" debate [PDF]

open access: yes, 2007
During recent years, a wide spectrum of research has questioned whether public services/infrastructure procurement through private finance, as exemplified by the UK Private Finance Initiative (PFI), meets minimum standard of democratic accountability ...
Asenova, D., Beck, M.
core  

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

open access: yesAdvanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang   +8 more
wiley   +1 more source

Enhancing organizational well-being and growth: The value of ombud services and the development of ombud consultation evaluation survey

open access: yesJournal of Community Safety and Well-Being
The role of an organizational ombud (formerly ombudsman) is increasingly recognized as a significant contributor to fostering a healthy workplace environment. This specialized service offers an impartial, confidential, informal, and independent resource
Katy Kamkar, Mario Baril
doaj   +1 more source

Performance modeling of e-procurement workflow using Generalised Stochastic Petri net (GSPN) [PDF]

open access: yes, 2002
This paper proposes a Generalised Stochastic Petri net (GSPN) model representing a generic e-procurement workflow process. The model displays the dynamic behaviour of the system and shows the inter relationship of process activities. An analysis based on
Ku-Mahamud, Ku Ruhana   +2 more
core  

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

open access: yesAdvanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin   +15 more
wiley   +1 more source

Towards The Development of a Governance System for Central Purchasing Body Collaboration and Performance

open access: yesStandards
This article explores the relationship between local authorities (mainly municipal organisations) and a central purchasing body (CPB). It critiques, from an agency theory perspective, the difficulties in aligning socio-economic goals of multiple ...
Douwe J. P. van de Goorberg   +2 more
doaj   +1 more source

Small Business Set-asides in Procurement Auctions: An Empirical Analysis [PDF]

open access: yes
As part of public procurement, many governments adopt small business programs to pro- vide contract opportunities for businesses often with preferences for firms operated by mem- bers of groups designated as disadvantaged. The redistribution arising from
Jun Nakabayashi
core  

Extending the Carrel system to mediate in the organ and tissue allocation processes: a first approach [PDF]

open access: yes, 2002
In this paper we extend the formalization of Carrel, a virtual organization for the procurement of tissues for transplantation purposes, in order to model also the procurement of human organs for transplants. We will focus in the organ allocation process
Caballero, Francisco   +4 more
core   +1 more source

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

open access: yesAdvanced Science, EarlyView.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng   +11 more
wiley   +1 more source

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