Results 231 to 240 of about 817,490 (340)

NIR‐II Responsive Multifunctional Scaffold Enabling “Kill‐Modulation‐Build” Synergistic Therapy for Infectious Bone Defects

Advanced Science, EarlyView.
A novel multifunctional scaffold with photothermal effects is developed for infected bone defect repair. It facilitates angiogenesis and osteogenesis while eliminating bacteria through hyperthermia. Additionally, the scaffold promotes macrophage polarization from M1 to M2 via ROS scavenging, enhancing anti‐inflammatory activity. This study demonstrates
Qifei Yang, Shu Lou, Yuan Zhang, Zhurun Fang, Changyue Xing, Wentao Wang, Minxuan Han, Zhendong Wang, Ben Zhong Tang, Ming Zhang   +9 more
wiley   +1 more source

Nineteen-Year Evidence on Measles-Mumps-Rubella Immunization in Mexico: Programmatic Lessons and Policy Implications. [PDF]

Vaccines (Basel)
Romero-Feregrino R, Romero-Feregrino R, Romero-Cabello R, Muñoz-Cordero B, Madrigal-Alonso B, Rocha-Rocha VM.   +5 more
europepmc   +1 more source

Government procurement in Ecuador: analysis and perspective

, 2023
Wilson Eduardo Faz Cevallos, Lenin Estalin Fuentes Gavilanez, Mariela Hidalgo Mayorga, Katherine Geovanna Guerrero Arrieta   +3 more
openalex   +2 more sources

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Availability of essential medicines for non-communicable diseases: a scoping review of challenges and opportunities. [PDF]

BMJ Glob Health
Joosse IR, Mantel-Teeuwisse A, van den Ham HA, Cantarero Arevalo L.   +3 more
europepmc   +1 more source

Challenges and drivers of green procurement among construction practitioners in Malaysia / Zafikha Aida Bidin ... [et al.] [PDF]

, 2020
Zafikha Aida Bidin, Asmah Alia Mohamad Bohari, S L A Rais, Munira Mohamad Saferi, Ayokunle Olubunmi Olanipekun   +4 more
openalex  

Public managers’ valuation of secondary policy objectives in public procurement – results from a discrete choice experiment

, 2021
Amandine Lerusse, Steven Van de Walle
openalex   +2 more sources

SV2B Promotes the Progression of TFE3‐Rearranged Renal Cell Carcinoma by Interacting with HERC2 to Impede the Degradation of NF‐κB Subunits

Advanced Science, EarlyView.
TFE3‐rearranged renal cell carcinoma (TFE3‐RCC) lacks clearly defined diagnostic and therapeutic targets. SV2B, a TFE3 target gene, promotes TFE3‐RCC progression by activating the NF‐κB pathway. Targeted inhibition with padsevonil or Withaferin A effectively suppresses tumor progression.
Huayi Feng, Zhuang Xiong, Shaoqing Yu, Junxiao Liu, Shouqing Cao, Kan Liu, Xing Huang, Lequan Wen, Baojun Wang, Qingbo Huang, Tiejun Pan, Xu Zhang, Xin Ma, Xiubin Li   +13 more
wiley   +1 more source

Factors contributing to human and veterinary medicine shortages in developing countries: perspectives of suppliers and regulators in Namibia. [PDF]

Trop Med Health
Uahupirapi K, Shifotoka S, Nangombe V.
europepmc   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source