Results 241 to 250 of about 817,490 (340)

Identifying pathways to achieve diverse objectives of the National Essential Diagnostics List: developing an assessment framework based on field studies in Cambodia, Indonesia, Lao PDR, and the Philippines. [PDF]

Trop Med Health
Kanamori S, Egami Y, Shimizu E, Miyano S, Villanueva AFDR, Hashimoto N, Kiyohara H, Norizuki M, Uechi M, Koto-Shimada K, Ichimura Y, Fujita M.   +11 more
europepmc   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

cDCDD and Heart Procurement: Challenges from a French Critical Care Perspective. [PDF]

Transpl Int
Le Dorze M, Charpentier J, Cheisson G, Couret D, Ducos G, Zuber B.   +5 more
europepmc   +1 more source

DIGITAL FORMAT OF THE REGIONAL LOGISTIC SYSTEM OF PUBLIC PROCUREMENT

, 2020
Т. С. Тасуева, Vera V. Borisova
openalex   +1 more source

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

Advanced Science, EarlyView.
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li, Yang Liu, Zehao Cai, Kang Li, Shun Gao, Ailin Lan, Dan Shu, Kuan He, Xin Liu, Yang Peng, Shipeng Guo, Haochen Yu, Aishun Jin, Meiying Shen, Shengchun Liu   +14 more
wiley   +1 more source

Risk Analysis on the Equipment and Material Procurement Process of Engineering, Procurement, and Construction (EPC) Projects

, 2020
Mohammed Ali Berawi, Aryartha Soepardi, Mustika Sari   +2 more
openalex   +2 more sources

Luminescent Nanocucurbits Enable Spatiotemporal Co‐Delivery of Hydrophilic and Hydrophobic Chemotherapeutic Agents

Advanced Science, EarlyView.
A cucurbit‐shaped luminescent nanoparticle (nanocucurbit) is engineered through the self‐assembly of polypeptides conjugated with aggregation‐induced emission (AIE) fluorophore. The resulting nanocucurbit exhibits approximately two‐fold higher cellular internalization efficiency compared to its spherical counterparts.
Ping Wei, Yunshan Ding, Shangning Liu, Jinhui Jiang, Jinghua Chen   +4 more
wiley   +1 more source

The impacts of the national volume-based procurement policy on the chronic disease medication market in China's public hospitals: a case study of medications for diabetes. [PDF]

BMC Health Serv Res
Wang B, Xiao K, Xia H, Yu Q, Wang G, Huang R, Niu J, Luo L.   +7 more
europepmc   +1 more source

Information Security in the Field of E-Commerce, E-Procurement (Tendering)

, 2020
Oksana I. Safonchyk, Kateryna M. Hlyniana, С. В. Мазуренко   +2 more
openalex   +1 more source

Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells

Advanced Science, EarlyView.
Brief 10 min bursts of high frequency (10 MHz) vibrational mechanostimulation to stem cells are shown to activate their epigenetic machinery to condition their differentiation down an osteogenic lineage within just 3 days, which is much earlier than that with other forms of mechanostimuli, and without requiring any biochemical additives. Abstract Cells
Lizebona A. Ambattu, Blanca del Rosal, Carmelo Ferrai, Leslie Y. Yeo   +3 more
wiley   +1 more source